How to use the Mounjaro KwikPen: A comprehensive guide

Jump to: What you’ll need | Preparing the Mounjaro KwikPen | Injection technique | Storage guidelines | Managing common challenges

Learning to use Mounjaro KwikPen is an important step in your weight-loss journey. While self-injection might feel daunting at first, understanding the process and having clear guidance can help you feel more confident and in control of your treatment.

This comprehensive guide walks you through each stage of using your Mounjaro KwikPen, from initial preparation to proper storage, with expert guidance to support your journey.

What you’ll need

Before starting your injection routine, gather these essential items:

Your medication kit:

• Mounjaro KwikPen at room temperature
• New, unopened pen needle
• Alcohol swab
• Clean cotton ball or gauze
• Sharps disposal container for used needles

Having everything prepared before you begin helps create a calm, organised environment for your injection routine.

Preparing the Mounjaro KwikPen

Initial preparation

1. Remove your pen from the refrigerator 30 minutes before injecting
2. Wash your hands thoroughly with soap and water
3. Find a clean, well-lit space for your injection

Checking the medication

Inspect your pen carefully:

• Verify the name “Mounjaro” and the correct dose strength
• Check the expiration date
• Ensure the liquid is clear and free from particles
• Confirm the pen isn’t damaged

Setting up the pen

1. Remove the pen cap
2. Clean the red rubber seal with an alcohol swab
3. Take a new pen needle and remove the paper tab
4. Push the needle straight onto the pen and twist until it’s secure
5. Remove both the outer and inner needle shields
6. Keep the outer shield for safe needle disposal later

Injection technique

Priming your pen

This essential step ensures your pen works correctly:

1. Turn the dose knob until you see two clicks and the extended line appears
2. Hold the pen with the needle pointing upward
3. Tap the cartridge holder gently to collect air bubbles at the top
4. Press the dose knob and count to 5 while watching for medication to appear at the needle tip

Choosing your injection site

Select from these recommended areas:

• The abdomen (stomach): Stay at least 5 centimetres from your belly button
• Thighs: Use the upper and outer areas
• Upper arms: Recommended only with assistance from another person

Rotate your injection site weekly to maintain healthy tissue. While you can use the same general area, choose different spots within that area for each injection.

Administering your dose

1. Turn the dose knob until the [1] icon appears
2. Clean your chosen injection site with an alcohol swab
3. Allow the area to dry completely
4. Create a firm injection surface by gently pinching your skin
5. Insert the needle straight in at a 90-degree angle
6. Press and hold the dose knob while counting slowly to 5
7. Look for the [0] icon to confirm complete dose delivery
8. Remove the needle carefully

Post injection care

1. If you notice a small blood drop, gently press with clean gauze
2. Don’t rub the injection site
3. Carefully replace the outer needle shield
4. Unscrew the needle and dispose of it in your sharps container
5. Replace the pen cap securely

Storage guidelines

Unused pens

• Store in the refrigerator between 2°C to 8°C
• Keep in original packaging to protect from light
• Never freeze your medication
• Allow to reach room temperature before use

Used pens

• Can be stored at room temperature (up to 30°C)
• Keep away from direct heat and sunlight
• Never store with the needle attached
• Use within 30 days of first use
• Dispose of after four weekly doses

Managing common challenges

If you’re feeling anxious:

• Take slow, deep breaths before starting
• Consider having someone present for support
• Remember that most people become more confident with practice
• Focus on each step individually
• Remember it may feel uncomfortable, but it’s not harmful

Technical difficulties

If the pen is difficult to push:

• Try injecting more slowly
• Ensure you’re using a new needle
• Check you’re injecting at the correct angle
• Verify the medication is at room temperature

When to seek support

Contact your healthcare team if:

• You’re uncertain about any part of the process
• The pen appears damaged
• You can’t confirm full dose delivery
• You experience unusual injection site reactions

Essential safety reminders

• Always use a new needle for each injection
• Never share your pen with others
• Store medication safely away from children
• Follow proper sharps disposal guidelines
• Keep track of your injection schedule

Remember that your healthcare team can provide support and guidance as you become familiar with your injection routine.

Building confidence takes time, and it’s expected to have questions as you adjust to this new aspect of your health management.

If you’re a member of Second Nature, you can read through our helpful guides in the Medication tab or message your health coach if you need support.

Second Nature’s medication programmes

Second Nature has two medication-supported programmes: a Wegovy weight-loss programme and a Mounjaro weight-loss programme.

For peace of mind.

Second Nature has worked with the NHS for over 6 years, providing weight-loss programmes across the UK.

While our Wegovy and Mounjaro weight-loss programmes are private and not currently used by the NHS, we’ve built the programmes focusing on scientific evidence, patient safety, and data security.

We hope that our 6+ years of working with the NHS and building a track record of effective weight-loss results will give you peace of mind to give us a try.