Second Nature logo

US

GLP-1s

GLP-1s are a new class of weight loss injections proven to help people achieve significant weight loss by reducing appetite and improving insulin function. Learn what GLP-1s are, how they work, whether you should use them, and the possible side effects.
Rybelsus Private Prescriptions UK

GLP-1s

Rybelsus Private Prescriptions UK

You can buy Rybelsus from high street and online pharmacies in the UK if you're living with type 2 diabetes, but it's not available for weight loss.

The best fat-dissolving injections

GLP-1s

The best fat-dissolving injections

According to average weight loss in human clinical trials, the best fat-dissolving injection is Mounjaro (tirzepatide). Find out more here.

What is the best injection for obesity?

GLP-1s

What is the best injection for obesity?

Based on average weight loss from randomised controlled trials, the best injection for obesity is Mounjaro (tirzepatide). Find out more here.

How long can you stay on Mounjaro?

GLP-1s

How long can you stay on Mounjaro?

How long you can stay on Mounjaro depends on your weight loss goals and how well you tolerate the medication. Find out more here.

How long can I stay on Wegovy?

GLP-1s

How long can I stay on Wegovy?

You can stay on Wegovy for life if it's clinically appropriate and you don't experience side effects that impact your quality of life. Find out more.

Do I need to be on Wegovy for life?

GLP-1s

Do I need to be on Wegovy for life?

Most people won't need to be on Wegovy for life to maintain weight loss. However, some people with certain genetic differences may need to. Find out more.

The best weight-loss injections in 2024

GLP-1s

The best weight-loss injections in 2024

Based on data from randomised controlled trials, Mounjaro is the best weight-loss injection available in the UK in 2024. Where do Wegovy and Saxenda rank?

Saxenda Private Prescription UK

GLP-1s

Saxenda Private Prescription UK

Where can you buy a private prescription of Saxenda in the UK, which provider should you choose, and how much does it cost?

Will I regain weight if I stop using Wegovy?

GLP-1s

Will I regain weight if I stop using Wegovy?

Research has shown that weight regain after stopping Wegovy is significant, but it's not inevitable. Find out how to prevent weight regain here.

Should you feel ashamed using weight-loss injections?

GLP-1s

Should you feel ashamed using weight-loss injections?

No, you shouldn't feel ashamed about using weight-loss injections. Obesity is a disease that can be treated using pharmaceutical means.

Make losing weight feel Second Nature

The first step on your Second Nature journey is to take our health quiz.

Hand holding phone

As seen on

The GuardianThe TimesChannel 4The Sunday Telegraph
Evening Standard
Metro