Second Nature logo

US

GLP-1s

GLP-1s are a new class of weight loss injections proven to help people achieve significant weight loss by reducing appetite and improving insulin function. Learn what GLP-1s are, how they work, whether you should use them, and the possible side effects.
How much weight can I lose in a month on semaglutide?

GLP-1s

How much weight can I lose in a month on semaglutide?

You could lose around 5% of your body after one month on semaglutide, and 8% after two months. Find out more about Wegovy and semaglutide here.

Buy Orlistat online

GLP-1s

Buy Orlistat online

Orlistat is available over the counter in a 60 mg form or with a prescription for the 120 mg form from approved online pharmacies and weight loss clinics.

Wegovy vs Rybelsus

GLP-1s

Wegovy vs Rybelsus

Wegovy and Rybelsus are the same drug but administered differently. Their impact on weight loss also differs. Read our guide as we compare the medications.

Buy Trulicity online

GLP-1s

Buy Trulicity online

Trulicity is available from online from registered pharmacies for individuals living type 2 diabetes. Find out what the criteria are here.

Ozempic vs Trulicity

GLP-1s

Ozempic vs Trulicity

Ozempic is a more effective weight-loss injection than Trulicity, but neither are approved for weight loss in the UK. Find out more here.

Zepbound vs Wegovy

GLP-1s

Zepbound vs Wegovy

Zepbound and Wegovy are weight-loss injections that lower hunger to help us lose weight, but which one is more effective? Find out here.

How quickly do you lose weight on Zepbound?

GLP-1s

How quickly do you lose weight on Zepbound?

You start losing weight immediately on Zepbound. It works by helping you feel less hungry, so you eat less and lose weight. Find out more here.

Does semaglutide make you lose muscle instead of fat?

GLP-1s

Does semaglutide make you lose muscle instead of fat?

Does Wegovy lead to muscle loss? Despite research showing it might reduce lean mass during weight loss, whether this is coming from muscle is unclear.

Ozempic vs Rybelsus

GLP-1s

Ozempic vs Rybelsus

Ozempic and Rybelsus are medications approved for people living with type 2 diabetes in the UK. But, how do they compare? Find out in our guide here.

Why am I not losing weight on Wegovy?

GLP-1s

Why am I not losing weight on Wegovy?

There are many reasons why you're not losing weight on Wegovy. Read our guide outlining the three main reasons and what to do about it.

Make losing weight feel Second Nature

The first step on your Second Nature journey is to take our health quiz.

Hand holding phone

As seen on

The GuardianThe TimesChannel 4The Sunday Telegraph
Evening Standard
Metro